UKUFAKWA KWE-GELATIN KWI-BIOMEDICAL MATERIALS
IGelatin, i-biopolymer yendalo yendalo, isongezo sokutya esilungiselelwe yi-hydrolysis ephakathi kwamathambo ezilwanyana, izikhumba, i-tendon, i-tendon kunye nezikali.Akukho nto inokuthelekiswa nolu hlobo lwezinto eziphilayo kwi-gelatin, ngenxa ye-biodegradability yayo, i-biocompatibility efanelekileyo, i-gel kunye neendleko eziphantsi.Ke ngoko, i-gelatin isetyenziswe ngokubanzi njengesixhobo sokwenza amayeza emveli kwizinto ze-biomedical.
IgaziSubstitutes
Utofelo-gazi luyimfuneko kwiimeko ezininzi, njengotyando olungaphelelanga okanye ukopha okukhulu kakhulu.Nangona kunjalo, ukunqongophala komthombo wegazi, ulungelelwaniso lwegazi oluntsonkothileyo, kunye nomngcipheko wonikezelo lwegazi lwe-allogeneic nako kukuthintela ukwenzeka kwexesha, ukusebenza kunye nokhuseleko lonyango lweklinikhi kakhulu.Indlela yokutshintshwa kweplasma inokusombulula ezi ngxaki, ngoko inamandla amakhulu esicelo seklinikhi kunye nendawo yokuphucula ubugcisa.Ke ngoko, izixhobo zegelatin, ezifana ne-succinyl gelatin kunye ne-polygelatin peptide, zisetyenziswa kakhulu njengezinto ezithatha indawo yeplasma kwikliniki.I-gelatin plasma substitutes iya kusetyenziswa kwiimeko ezingxamisekileyo ezifana nokunciphisa umthamo wegazi kunye nokothuka.Ukungena kweColloid kunokwandisa umthamo wegazi kunye nokuphucula i-microcirculation.I-gelatin indawo yegazi ineenzuzo ezininzi, ezifana nokuthotywa, igalelo elikhulu, i-non-toxic, i-immunogenicity kunye nokunye.
HuchukuMizixhobo
Kwiminyaka yakutshanje, uluntu lwezonyango luye lwahlawula ingqalelo ngakumbi ekuphuhlisweni kwezinto ezintsha ze-hemostatic.Isiponji segelatin esifunxayo sitsale umdla kakhulu kuba sineengenelo zesiphumo esihle se-hemostatic, ixabiso eliphantsi kunye nokuqhubekeka okunamandla.I-hemostatic mechanism ye-gelatin hemostatic sponge ikakhulu ukuvelisa isakhiwo se-reticular ngokuthintela imithambo yegazi, ukuze i-agglutinate platelets kunye ne-deposit fibrinogen.Oku kunenzuzo kakhulu ekubunjweni kwe-thrombosis, ukwenzela ukunciphisa ixesha lokudibanisa kwaye ekugqibeleni uyeke ukopha.Ngokwendlela yokudibanisa, i-gelatin hemostatic sponge inemisebenzi ephambili yoxinzelelo lomatshini kunye nokufunxa amanzi.Kuyo yonke inkqubo ye-coagulation, umzekelo, ayidlali indima ebalulekileyo ekukhuthazeni ukuveliswa kweenkqubo ezibalulekileyo ze-hemostatic ezifana nokusebenza kweprothrombin.Isiponji esifunxayo esixhaphakileyo segelatin esisetyenziswa ekliniki sinezinto ezininzi ezingeloncedo, njengokusabela okukhulu kwezicubu zangaphandle, ukusebenza kakuhle okuphantsi kwe-hemostatic kunye nokuwa ngokulula.Okwangoku, i-gelatin isoloko iguqulwa okanye idityaniswe nezinye izinto ukuvelisa izixhobo ze-hemostatic kunye nokusebenza kakuhle.
OkunyeAizicelo
I-Gelatin ubukhulu becala ivela kwi-collagen kwizicubu zomzimba, ngoko ke ineempawu ezibalaseleyo zebhayoloji, ezinje nge-biocompatibility elungileyo kunye ne-biodegradability, ke isetyenziswe ngokubanzi kwintsimi ye-biomedical.I-Gelatin ingasetyenziselwa kuphela kule miba ingentla, kodwa kunye nokunyangwa kwezifo zesikhumba.Ngokomzekelo, i-gelatin ye-hydrolyzed inokunyanga isikhumba esiqhekezayo, i-ichthyosis kunye ne-dandruff.Ngaphezu koko, i-gelatin nayo isetyenziswe ngokubanzi kumayeza angaphakathi.Kwi-Pharmacopoeia yaseTshayina, kuchazwa ukuba i-gelatin ye-macromolecular ineempembelelo zokomisa okumanzi kunye nokuvelisa igazi, kwaye ineziphumo ezithile zokunyanga kwiimpawu ezininzi ezifana ne-anemia kunye nokulahlekelwa kwegazi.I-gelatin ene-hydrolyzed nayo inefuthe elicacileyo kunyango lwe-gastritis engapheliyo kunye nezinye iimpawu.
Ixesha lokuposa: Aug-11-2021
