IINGQONDO EZINTATHU EZINGAQONDIYO NGECOLAGEN
Okokuqala, kudla ngokuthiwa "i-collagenayingomthombo ulungileyo weprotheyini kwisondlo sezemidlalo."
Ngokuphathelele izondlo ezisisiseko, i-collagen ngamanye amaxesha ihlelwa njengomthombo weproteni ongaphelelanga ngokweendlela zangoku zokuvavanya umgangatho weproteni ngenxa yokuba incinci kwi-amino acids ezibalulekileyo. Nangona kunjalo, indima ye-collagen esebenzayo kwi-bioactive idlula indima yesondlo esisiseko yeproteni ngokubhekisele ekunikeleni ii-amino acids ezibalulekileyo ukuhlangabezana neemfuno zemihla ngemihla. Ngenxa yesakhiwo sayo se-peptide esahlukileyo, ii-bioactive collagen peptides (BCP) zibopha kwii-receptors ezithile zeseli kwaye zikhuthaze ukuveliswa kweeproteni ze-extracellular matrix. Isiphumo sayo asinanto yakwenza ne-essential amino acid spectrum okanye amanqaku omgangatho weproteni ye-collagen.
Okwesibini, abathengi badidekile malunga nokuhlelwa kwee-collagen peptides.
Ukusasazwa kwe-collagen emzimbeni kuyinkimbinkimbi. Kodwa nokuba zikuphi na, ukuhlelwa kweentlobo ze-collagen (ezingama-28 sele zichongiwe ukuza kuthi ga ngoku) akuchaphazeli ukusebenza kwee-peptides zazo ze-collagen njengomthombo wesondlo. Umzekelo, ngokwezilingo ezahlukeneyo zangaphambi kweklinikhi, i-collagen yohlobo I kunye nohlobo II zibonisa phantse ulandelelwano olufanayo lweproteni (malunga nama-85%), kwaye xa i-collagen yohlobo I kunye nohlobo II zi-hydrolyzes zibe zii-peptides, umahluko wazo awunampembelelo ekusebenzeni kwee-peptides ze-collagen okanye ekuvuseleleni iiseli.
Okwesithathu, ii-peptides ze-collagen zebhayoloji azikhuselekanga ekugayweni kwe-enzyme emathunjini.
Xa kuthelekiswa nezinye iiproteni, i-collagen inesakhiwo se-amino acid esahlukileyo esenza kube lula ukuthuthwa kwee-peptides eziphilayo kudonga lwamathumbu. Xa kuthelekiswa nolwakhiwo lwe-α helical lwezinye iiproteni, ii-peptides ze-collagen zebhayoloji zinesakhiwo eside, esincinci kwaye ziyamelana ngakumbi ne-hydrolysis yamathumbu. Le propati yenza ukuba ibe luncedo ekufunxeni kakuhle nasekuzinzeni kwamathumbu.
Namhlanje, ukusetyenziswa kudlula kwiimfuno ezisisiseko kwaye kugxile kwii-amino acid ezibalulekileyo ezixhomekeke kwiimeko ezithile kunye neekhompawundi zokutya ezisebenzayo njengee-metabolism controllers ezinokuzisa iingenelo zempilo ezilungileyo nezihlala ixesha elide emzimbeni kwaye zihlangabezane neemfuno ezithile zomzimba ezifana nokulwa nokwaluphala kunye nokunciphisa ukwenzakala kwezemidlalo. Ngokuphathelele ukuqonda kwabathengi, i-collagen ibe ngomnye wemithombo ephambili yeepeptides ezisebenzayo.
Ixesha lokuthumela: Septemba-15-2021
