Ikhaya

 

I-Collagenyinxalenye ephambili ye-extracellular matrix (ECM), efumaneka ikakhulu kulusu lomntu, emathanjeni, kwi-cartilage, emazinyweni, kwimisipha, kwi-ligaments, nakwimithambo yegazi. Ikwayiproteni ebalulekileyo yesakhiwo sezicubu ezidityanisiweyo.

I-Collagen yinxalenye ephambili yedermis yolusu lomntu. Kunye nenani elincinci le-elastin, yenza uthungelwano oluqhelekileyo lwee-collagen fibers, olunika ulusu ukuqina kunye nokuqina kwaye luvumela umaleko we-epidermal ukuba uthuthe umswakama.

Nangona kunjalo, izinto ezinje ngokwaluphala, imitha ye-UV, ukutshaya, kunye nendlela yokuphila engeyiyo esempilweni zibangela ukuba i-collagen inciphe. Xa i-collagen ilahleka ngobuninzi, iimpawu zokwaluphala ezifana nokulahlekelwa kukuqina kwesikhumba, ukugoba, imibimbi, umbala, ukoma, ulusu olurhabaxa, kunye nolusu olunobuthathaka ziyavela kancinci kancinci.

Ngoko ke, xa i-collagen incipha, ngaba iimveliso ze-collagen zomlomo zinokuyicothisa inkqubo yokwaluphala?

Ngaba iipeptides ze-collagen zomlomo zinokufunxwa ngumzimba?

Iimveliso ze-collagen eziqhelekileyo ezithengiswayo zibhekisa kwii-collagen peptides, hayi kwi-collagen.

I-CollagenIipeptides zingumxube weepeptides ezinobunzima obuphantsi beemolekyuli ezinobunzima obuphakathi kwe-2000 ukuya kwi-10,000 Da ezifakwe kwi-collagen (300,000 Da). Xa kuthelekiswa ne-collagen enobunzima obukhulu beemolekyuli, iipeptides ze-collagen zinobunzima obuncinci beemolekyuli kwaye zigaywa kwaye zifunxwe lula.

Ukongeza, ii-dipeptides kunye nee-tripeptides ezikwi-collagen peptides zithuthwa ngqo kwaye zifunxwe njengee-peptides yi-oligopeptide transporter protein (PepT1) ekhoyo kwiiseli ze-epithelial zamathumbu amancinci. Zinokujoliswa kwiindawo ezithile emzimbeni ukuze zisebenze kakuhle kwaye zisebenze kakuhle.

UWatanabe-Kamiyama M. nabanye batya iipeptide ze-collagen ezine-14C ezibhalwe kwizitho ezahlukeneyo zeempuku baza babona ukusasazeka kwazoiipeptides ze-collagen.

Olu phononongo lubonise ukuba iipeptides ze-collagen zomlomo zisasazwa kumalungu abalulekileyo emzimbeni wonke emva kokugaya nokufunxwa, kwaye zibekwe ngokukodwa kwizicubu ezityebileyo ze-collagen, ingakumbi ulusu, emva kwexesha elithile.

Ngaba ii-Oral Collagen Peptides Zingaphucula Iimeko Zolusu?

Kwiminyaka yakutshanje, uphando oluninzi luye lwaqinisekisa imiphumo emihle ye-collagen peptides yomlomo ekulibaziseni ukuguga kolusu kunye nokuvuselela ulusu.

Abaphandi bakhethe abantu abangama-64 abaneminyaka engama-40 ukuya kwengama-60 ubudala ukuba bathathe i-1000 mg yee-collagen peptides eziphantsi kobunzima beemolekyuli ngomlomo imihla ngemihla kangangeeveki ezili-12 baza bafumanisa ukuba emva kweeveki ezi-6 zokusetyenziswa, ukufuma kolusu kuphuculwe kakhulu, kwaye emva kweeveki ezili-12, imibimbi kunye nokuqina kolusu kuphuculwe, okubonisa iziphumo zokulwa nokwaluphala. Iziphumo zibonise ukuphucuka okukhulu ekugcinweni komswakama kolusu emva kweeveki ezi-6 zokusetyenziswa kunye nefuthe lokulwa nokwaluphala emva kweeveki ezili-12.